Variant Haemoglobins

A Guide to Identification

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  • Variant
  • Haemoglobins
  • A
  • Guide
  • to
  • Identification
  • is
  • based
  • on
  • the
  • premise
  • that
  • any
  • single
  • diagnostic
  • technique
  • offers
  • only
  • a
  • very
  • provisional
  • identification
  • of
  • a
  • variant
  • haemoglobin.
  • In
  • routine
  • diagnostic
  • practice
  • two
  • techniques
  • are
  • needed
  • as
  • a
  • minimum,
  • with
  • the
  • results
  • being
  • interpreted
  • in
  • the
  • light
  • of
  • the
  • clinical
  • details,
  • blood
  • count,
  • blood
  • film
  • and
  • ethnic
  • origin.
  • This
  • book
  • covers
  • 150
  • normal
  • and
  • variant
  • haemoglobins
  • that
  • have
  • been
  • studied
  • and
  • carefully
  • documented.Variant
  • Haemoglobins
  • has
  • four
  • introductory
  • chapters
  • followed
  • by
  • an
  • invaluable
  • atlas.
  • The
  • introductory
  • chapters
  • coverThe
  • atlas
  • section
  • comprises
  • 170
  • full
  • colour
  • pages
  • in
  • which
  • each
  • variant
  • haemoglobin
  • or
  • combination
  • of
  • haemoglobins
  • is
  • illustrated
  • by
  • cellulose
  • acetate
  • electrophoresis
  • at
  • alkaline
  • pH,
  • agarose
  • gel
  • electrophoresis
  • at
  • acid
  • pH,
  • isoelectric
  • focusing
  • and
  • one
  • or
  • more
  • HPLC
  • traces.
  • For
  • ease
  • of
  • reference,
  • the
  • atlas
  • pages
  • are
  • arranged
  • according
  • to
  • the
  • retention
  • time
  • of
  • each
  • haemoglobin
  • on
  • HPLC,
  • this
  • becoming
  • increasingly
  • the
  • primary
  • technique
  • employed
  • in
  • haemoglobin
  • identification.Bringing
  • a
  • mix
  • of
  • necessary
  • scientific
  • expertise
  • and
  • clinical
  • knowledge,
  • each
  • author
  • has
  • more
  • than
  • 30
  • years
  • experience
  • in
  • the
  • diagnosis
  • of
  • variant
  • haemoglobins.Providing
  • otherwise
  • unavailable
  • information,
  • this
  • unique
  • and
  • practical
  • guideA
  • remarkably
  • useful
  • book,
  • Variant
  • Haemoglobins
  • will
  • be
  • valuable
  • for
  • haematopathologists,
  • clinical
  • and
  • laboratory
  • haematologists
  • in
  • practice
  • and
  • in
  • training
  • and
  • all
  • laboratory
  • staff
  • involved
  • in
  • haemoglobinopathy diagnosis.
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