Antibacterial Agents

Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications

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  • Antibacterial
  • agents
  • act
  • against
  • bacterial
  • infection
  • either
  • by
  • killing
  • the
  • bacterium
  • or
  • by
  • arresting
  • its
  • growth.
  • They
  • do
  • this
  • by
  • targeting
  • bacterial
  • DNA
  • and
  • its
  • associated
  • processes,
  • attacking
  • bacterial
  • metabolic
  • processes
  • including
  • protein
  • synthesis,
  • or
  • interfering
  • with
  • bacterial
  • cell
  • wall
  • synthesis
  • and
  • function.Antibacterial
  • Agents
  • is
  • an
  • essential
  • guide
  • to
  • this
  • important
  • class
  • of
  • chemotherapeutic
  • drugs.
  • Compounds
  • are
  • organised
  • according
  • to
  • their
  • target,
  • which
  • helps
  • the
  • reader
  • understand
  • the
  • mechanism
  • of
  • action
  • of
  • these
  • drugs
  • and
  • how
  • resistance
  • can
  • arise.
  • The
  • book
  • uses
  • an
  • integrated
  • “lab-to-clinic”
  • approach
  • which
  • covers
  • drug
  • discovery,
  • source
  • or
  • synthesis,
  • mode
  • of
  • action,
  • mechanisms
  • of
  • resistance,
  • clinical
  • aspects
  • (including
  • links
  • to
  • current
  • guidelines,
  • significant
  • drug
  • interactions,
  • cautions
  • and
  • contraindications),
  • prodrugs
  • and
  • future
  • improvements.Agents
  • covered
  • include:Antibacterial
  • Agents
  • will
  • find
  • a
  • place
  • on
  • the
  • bookshelves
  • of
  • students
  • of
  • pharmacy,
  • pharmacology,
  • pharmaceutical
  • sciences,
  • drug
  • design/discovery,
  • and
  • medicinal
  • chemistry,
  • and
  • as
  • a
  • bench
  • reference
  • for
  • pharmacists
  • and
  • pharmaceutical
  • researchers
  • in
  • academia
  • and industry.
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